Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10203633 | 0.88 | GCK (0.69) | GCKKCNH2 | |
| SCHEMBL1140968 | 0.87 | GCK (0.81) | GCKKCNH2 | |
| SCHEMBL16473218 | 0.82 | GCK (0.81) | GCKKCNH2 | |
| SCHEMBL16473166 | 0.81 | GCK (0.76) | GCKKCNH2 | |
| SCHEMBL1132358 | 0.78 | GCK (0.73) | GCKKCNH2 | |
| SCHEMBL12021036 | 0.77 | GCK (0.84) | GCKKCNH2 | |
| SCHEMBL1107470 | 0.77 | GCK (0.86) | GCKKCNH2 | |
| SCHEMBL16473167 | 0.76 | GCK (0.66) | GCKKCNH2 | |
| SCHEMBL1107463 | 0.76 | GCK (0.87) | GCKKCNH2 | |
| SCHEMBL1107337 | 0.76 | GCK (0.60) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008005964-A2 | PHOSPHONATE AND PHOSPHINATE COMPOUNDS AS GLUCOKINASE ACTIVATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-10 | — | — | WO | disclosed |