Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 19/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4878457 | 1.00 | GCK (0.50) | GCK | |
| SCHEMBL4878454 | 1.00 | GCK (0.50) | GCK | |
| SCHEMBL4181636 | 0.87 | GCK (0.65) | GCK | |
| SCHEMBL4875197 | 0.85 | GCK (0.51) | GCK | |
| SCHEMBL2669198 | 0.85 | GCK (0.51) | GCK | |
| SCHEMBL4875191 | 0.85 | GCK (0.51) | GCK | |
| SCHEMBL14216768 | 0.85 | GCK (0.51) | GCK | |
| SCHEMBL2510964 | 0.85 | GCK (0.51) | GCK | |
| SCHEMBL2510963 | 0.85 | GCK (0.51) | GCK | |
| SCHEMBL2652154 | 0.84 | GCK (0.64) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293741-A1 | Tricyclo Substituted Amides as Glucokinase Modulators | PROSIDION LIMITED (GB) | 2008-11-27 | — | — | US | disclosed |
| US-20080293741-A1 | Tricyclo Substituted Amides as Glucokinase Modulators | PROSIDION LIMITED (GB) | 2008-11-27 | — | — | US | disclosed |
| WO-2007051847-A1 | TRICYCLO SUBSTITUTED AMIDES AS GLUCOKINASE MODULATORS | PROSIDION LTD (GB) | 2007-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293741-A1 | Tricyclo Substituted Amides as Glucokinase Modulators | GCK, GCKR, GALK1 | GCK 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.