Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9892940 | 0.94 | GCK (0.68) | GCK | |
| SCHEMBL2668910 | 0.86 | GCK (0.66) | GCK | |
| SCHEMBL1139499 | 0.79 | GCK (0.66) | GCK | |
| SCHEMBL1137351 | 0.78 | GCK (0.57) | GCK | |
| SCHEMBL2662084 | 0.77 | GCK (0.73) | GCK | |
| SCHEMBL2659754 | 0.77 | GCK (0.73) | GCK | |
| SCHEMBL2651513 | 0.76 | GCK (1.00) | GCK | |
| SCHEMBL2650223 | 0.76 | GCK (1.00) | GCK | |
| SCHEMBL3389490 | 0.75 | GCK (0.74) | GCK | |
| SCHEMBL1140713 | 0.75 | GCK (0.64) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008005964-A2 | PHOSPHONATE AND PHOSPHINATE COMPOUNDS AS GLUCOKINASE ACTIVATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-10 | — | — | WO | disclosed |