Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071288 | 0.91 | GCK (0.79) | GCKKCNH2CYP2C9 | |
| SCHEMBL9071286 | 0.91 | GCK (0.74) | GCKKCNH2CYP2C9 | |
| SCHEMBL1134324 | 0.89 | GCK (1.00) | GCKKCNH2 | |
| SCHEMBL1133774 | 0.89 | GCK (1.00) | GCKKCNH2 | |
| SCHEMBL1132791 | 0.89 | GCK (1.00) | GCKKCNH2 | |
| SCHEMBL1107344 | 0.85 | GCK (0.84) | GCKKCNH2 | |
| SCHEMBL16473165 | 0.84 | GCK (0.59) | GCKKCNH2CYP2C9 | |
| SCHEMBL1107715 | 0.82 | GCK (0.66) | GCKKCNH2 | |
| SCHEMBL1107643 | 0.82 | GCK (0.66) | GCKKCNH2 | |
| SCHEMBL1133395 | 0.82 | GCK (1.00) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008005964-A2 | PHOSPHONATE AND PHOSPHINATE COMPOUNDS AS GLUCOKINASE ACTIVATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-10 | — | — | WO | disclosed |