Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 17/20 | 0.53 |
| ▸ | ADCY6 | O43306 | 5/20 | 0.51 |
| ▸ | ADCY3 | O60266 | 5/20 | 0.51 |
| ▸ | ADCY9 | O60503 | 5/20 | 0.51 |
| ▸ | ADCY5 | O95622 | 5/20 | 0.51 |
| ▸ | ADCY8 | P40145 | 5/20 | 0.51 |
| ▸ | ADCY7 | P51828 | 5/20 | 0.51 |
| ▸ | ADCY2 | Q08462 | 5/20 | 0.51 |
| ▸ | ADCY1 | Q08828 | 5/20 | 0.51 |
| ▸ | ADCY4 | Q8NFM4 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657077 | 0.87 | GCGR (0.60) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2658990 | 0.79 | GCGR (0.51) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2656673 | 0.79 | MEN1 (0.52) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL21528960 | 0.77 | GCGR (0.60) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL21528961 | 0.77 | GCGR (0.60) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL1765472 | 0.76 | GCGR (0.57) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2654861 | 0.76 | GCGR (0.61) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2658181 | 0.74 | GCGR (0.53) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL1765376 | 0.74 | GCGR (0.73) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2657984 | 0.74 | GCGR (0.64) | GCGRADCY6ADCY3ADCY9ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007123581-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-11-01 | — | — | WO | disclosed |