Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 10/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 4/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2513922 | 0.90 | GCK (0.47) | GCK | |
| SCHEMBL2657005 | 0.83 | GCK (0.52) | GCK | |
| SCHEMBL2511691 | 0.73 | GCK (0.47) | GCK | |
| SCHEMBL2513138 | 0.72 | GCK (0.49) | GCK | |
| SCHEMBL2513120 | 0.71 | GCK (0.51) | GCK | |
| SCHEMBL2515382 | 0.70 | GCK (0.51) | GCK | |
| SCHEMBL2517251 | 0.69 | GCK (0.53) | GCK | |
| SCHEMBL2517324 | 0.68 | GCK (0.49) | GCK | |
| SCHEMBL2516230 | 0.68 | GCK (0.64) | GCK | |
| SCHEMBL2517274 | 0.68 | GCK (0.64) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104034-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-09-13 | — | — | WO | disclosed |