Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 14/20 | 0.54 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12228084 | 0.82 | GCK (0.81) | GCK | |
| SCHEMBL2514499 | 0.75 | GCK (0.73) | GCKALDH1A1 | |
| SCHEMBL17335956 | 0.73 | GCK (0.52) | GCKFEN1ALDH1A1 | |
| SCHEMBL2514393 | 0.71 | GCK (1.00) | GCK | |
| SCHEMBL11871647 | 0.70 | FEN1 (0.55) | FEN1ALDH1A1MTOROPRL1OPRM1 | |
| SCHEMBL2669078 | 0.69 | GCK (0.73) | GCK | |
| SCHEMBL9072908 | 0.69 | GCK (0.64) | GCKALDH1A1 | |
| SCHEMBL9072911 | 0.69 | GCK (0.73) | GCKFEN1ALDH1A1 | |
| SCHEMBL11865926 | 0.69 | FEN1 (0.60) | FEN1ALDH1A1 | |
| SCHEMBL12228041 | 0.69 | GCK (0.65) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104034-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-09-13 | — | — | WO | disclosed |