SCHEMBL2669332

SCHEMBL2669332

CN/N=C\C(=N)NC(=O)c1cc(Oc2ccc(S(=O)(=O)C3CC3)cc2)c2c(c1)OC(C)(COC)C2

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 12/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2669383 0.84 GCK (0.41) GCK
SCHEMBL2644305 0.83 GCK (0.37) GCK
SCHEMBL644008 0.80 GCK (0.53) GCK
SCHEMBL2669362 0.80 GCK (0.38) GCK
SCHEMBL643948 0.79 GCK (0.36) GCK
SCHEMBL644962 0.78 GCK (0.49) GCK
SCHEMBL2645495 0.74 GCK (0.44) GCK
SCHEMBL9923392 0.74 GCK (0.40) GCK
SCHEMBL2644171 0.72 GCK (0.39) GCK
SCHEMBL644591 0.72 GCK (0.40) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007122482-A1 FUSED PHENYL AMIDO HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOKINASE-MEDIATED DISEASES PFIZER PRODUCTS INC. (US) 2007-11-01 WO disclosed