⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31574391 | 1.00 | — | — | |
| SCHEMBL31440928 | 0.81 | — | — | |
| SCHEMBL6626278 | 0.81 | — | — | |
| SCHEMBL6627334 | 0.79 | — | — | |
| SCHEMBL3131735 | 0.79 | — | — | |
| SCHEMBL11513963 | 0.75 | — | — | |
| SCHEMBL15203393 | 0.75 | — | — | |
| SCHEMBL17703502 | 0.75 | — | — | |
| SCHEMBL17533890 | 0.75 | — | — | |
| SCHEMBL13727704 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084776-A | Synthesis method of substituted pyridine compound | 山东莱福科技发展有限公司 | 2024-05-28 | — | — | CN | claimed |
| JP-7102051-A | — | — | None | — | — | JP | disclosed |
| CN-118084776-A | Synthesis method of substituted pyridine compound | 山东莱福科技发展有限公司 | 2024-05-28 | — | — | CN | disclosed |
| EP-3272738-A2 | PROCESSES FOR PREPARING JAK INHIBITORS AND RELATED INTERMEDIATE COMPOUNDS | Incyte Holdings Corporation (US) | 2018-01-24 | — | — | EP | disclosed |
| US-8431713-B2 | 2-aminopyridine derivatives as glucokinase activators | ARRAY BIOPHARMA, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20100099713-A1 | 2-AMINOPYRIDINE DERIVATIVES AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2010-04-22 | — | — | US | disclosed |
| US-7557216-B2 | Process for production of 5-chloro-2,4-dihydroxypyridine | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2009-07-07 | — | — | US | disclosed |
| US-20090043101-A1 | PROCESS FOR PRODUCTION OF 5-CHLORO-2,4-DIHYDROXYPYRIDINE | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2009-02-12 | — | — | US | disclosed |
| WO-2008091770-A1 | 2-AMINOPYRIDINE DERIVATIVES AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2008-07-31 | — | — | WO | disclosed |
| EP-0591105-B1 | Bisazo, bisazomethine and azo-azomethine compounds | CIBA SC HOLDING AG (CH) | 2001-10-24 | — | — | EP | disclosed |
| JP-H07102051-A | FUNCTIONAL-AMINE POLYESTER POLYMER | XEROX CORP | 1995-04-18 | — | — | JP | disclosed |
| US-5155113-A | Administering 5-fluorouracil and derivatives with pyridine and pyridone derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0180188-B1 | A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |
| US-4672125-A | Chlorination of β-methylpyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1987-06-09 | — | — | US | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |