Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16591260 | 1.00 | KDM1A (0.60) | KDM1ASLC6A3SLC6A2SLC6A4HTR2A | |
| SCHEMBL2615237 | 1.00 | KDM1A (0.60) | KDM1ASLC6A3SLC6A2SLC6A4HTR2A | |
| SCHEMBL21503486 | 1.00 | KDM1A (0.60) | KDM1ASLC6A3SLC6A2SLC6A4HTR2A | |
| SCHEMBL16234254 | 1.00 | KDM1A (0.60) | KDM1ASLC6A3SLC6A2SLC6A4HTR2A | |
| SCHEMBL12876074 | 1.00 | KDM1A (0.60) | KDM1ASLC6A3SLC6A2SLC6A4HTR2A | |
| SCHEMBL2615236 | 1.00 | KDM1A (0.60) | KDM1ASLC6A3SLC6A2SLC6A4HTR2A | |
| SCHEMBL14101959 | 1.00 | KDM1A (0.60) | KDM1ASLC6A3SLC6A2SLC6A4HTR2A | |
| Ammonia Solution, Strong SCHEMBL7928878 | 0.98 | KDM1A (0.58) | KDM1ASLC6A3SLC6A2SLC6A4HTR2A | |
| SCHEMBL13391042 | 0.84 | KDM1A (0.46) | KDM1ASLC6A3SLC6A2SLC6A4HTR2A | |
| SCHEMBL13379965 | 0.84 | KDM1A (0.46) | KDM1ASLC6A3SLC6A2SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784669-B1 | PTERIDINONE COMPOUNDS AND USES THEREOF | VERTEX PHARMA (US) | 2023-10-25 | — | — | EP | disclosed |