Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | KIF5B | P33176 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3537413 | 0.80 | BRD4 (0.48) | BRD4IDO1AXLMETAP2RET | |
| SCHEMBL1963674 | 0.79 | CSNK2A1 (0.48) | BRD4IDO1AXLMETAP2RET | |
| SCHEMBL30861139 | 0.79 | CSNK2A1 (0.48) | BRD4IDO1AXLMETAP2RET | |
| SCHEMBL1965644 | 0.79 | BRD4 (0.47) | BRD4IDO1AXLMETAP2RET | |
| SCHEMBL25799617 | 0.79 | BRD4 (0.47) | BRD4IDO1AXLMETAP2RET | |
| SCHEMBL31411430 | 0.79 | BRD4 (0.47) | BRD4IDO1AXLMETAP2RET | |
| SCHEMBL23979717 | 0.76 | BRD4 (0.44) | BRD4IDO1AXLMETAP2RET | |
| SCHEMBL17030771 | 0.76 | BRD4 (0.44) | BRD4IDO1AXLMETAP2RET | |
| SCHEMBL19304040 | 0.76 | BRD4 (0.44) | BRD4IDO1AXLMETAP2RET | |
| SCHEMBL16647168 | 0.76 | IDO1 (0.47) | IDO1AXLMETAP2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009128481-A1 | NITROGENATED 5-MEMBERED HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-22 | — | — | WO | disclosed |