Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 1.00 |
| ▸ | FLT1 | P17948 | 17/20 | 1.00 |
| ▸ | FLT4 | P35916 | 17/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15962804 | 0.92 | KDR (1.00) | KDRFLT1FLT4 | |
| SCHEMBL24520230 | 0.90 | KDR (0.82) | KDRFLT1FLT4 | |
| SCHEMBL15962801 | 0.90 | KDR (0.82) | KDRFLT1FLT4 | |
| SCHEMBL15962799 | 0.90 | KDR (0.93) | KDRFLT1FLT4 | |
| SCHEMBL26697286 | 0.89 | FLT1 (1.00) | KDRFLT1FLT4 | |
| SCHEMBL5653965 | 0.88 | KDR (0.78) | KDRFLT1FLT4 | |
| SCHEMBL26697202 | 0.88 | FLT1 (1.00) | KDRFLT1FLT4 | |
| SCHEMBL15962835 | 0.88 | KDR (0.79) | KDRFLT1FLT4 | |
| SCHEMBL5201472 | 0.88 | FLT1 (0.85) | KDRFLT1FLT4 | |
| SCHEMBL29757950 | 0.87 | FLT1 (0.92) | KDRFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226323-A1 | QUINAZOLINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 天津济坤医药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |
| WO-2023226323-A1 | QUINAZOLINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 天津济坤医药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |