SCHEMBL2669770

SCHEMBL2669770

C/C=C(/OC(CC)CC)c1ccc(-c2cc(Oc3cnc(S(C)(=O)=O)cn3)cc(O[C@@H](C)CO)c2)[nH]1

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 18/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2669694 0.91 GCK (0.37) GCK
SCHEMBL2669600 0.88 GCK (0.42) GCK
SCHEMBL9071144 0.85 GCK (0.45) GCK
SCHEMBL2669687 0.85 GCK (0.43) GCK
SCHEMBL2669663 0.83 GCK (0.39) GCK
SCHEMBL12265454 0.80 GCK (0.35) GCK
SCHEMBL423831 0.79 GCK (0.48) GCK
SCHEMBL2669587 0.78 GCK (0.40) GCK
SCHEMBL421638 0.78 GCK (0.40) GCK
SCHEMBL12266083 0.77 GCK (0.36) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009099080-A1 NOVEL PHENYLPYRROLE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-08-13 WO disclosed