SCHEMBL2669795

SCHEMBL2669795

C=C(O)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15074897 0.76
SCHEMBL13893139 0.73
SCHEMBL8104886 0.73
SCHEMBL17937333 0.73
SCHEMBL13075722 0.73
SCHEMBL21093502 0.73
SCHEMBL27245 0.72
SCHEMBL3261400 0.70
SCHEMBL14204503 0.70
SCHEMBL776535 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037344-B2 NLRP3 modulators INNATE TUMOR IMMUNITY, INC (US) 2024-07-16 US disclosed
EP-4353235-A2 NLRP3 MODULATORS Innate Tumor Immunity, Inc. (US) 2024-04-17 EP disclosed
US-11806404-B2 Site specific homogeneous with KSP inhibitors BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2023-11-07 US disclosed
WO-2023156510-A1 METHOD FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE F. HOFFMANN-LA ROCHE AG (CH) 2023-08-24 WO disclosed
WO-2023148129-A1 IMIDAZOLE MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. HOFFMANN-LA ROCHE AG (CH) 2023-08-10 WO disclosed
WO-2023144160-A1 NEW HETEROCYCLIC COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2023-08-03 WO disclosed
EP-3794002-B1 COMPOUNDS ENTERPRISE THERAPEUTICS LTD (GB) 2023-08-02 EP disclosed
CN-114667285-A Antiviral pyrazolopyridinone compounds 诺华股份有限公司 2022-06-24 CN disclosed
EP-3697788-B1 BIS(PENTAHYDROXYHEXYL)AMINO SUBSTITUTED 2-{[(3-AMINO-PYRAZIN-2-YL)FORMAMIDO]METHYL}-1H-1,3-BENZODIAZOL-3-IUM DERIVATIVES AS ENAC INHIBITORS FOR TREATING RESPIRATORY DISEASES ENTERPRISE THERAPEUTICS LTD (GB) 2021-12-15 EP disclosed
EP-3888657-A1 HETEROCYCLYLAMINES AS PI3K INHIBITORS Incyte Holdings Corporation (US) 2021-10-06 EP disclosed
WO-2007031428-A1 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2007-03-22 WO disclosed
WO-2007025776-A2 CYSTEINE PROTEASE INHIBITORS GLAXO GROUP LIMITED (GB) 2007-03-08 WO disclosed
WO-2007017092-A1 SUBSTITUTED 4-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES BAYER HEALTHCARE AG (DE) 2007-02-15 WO disclosed
EP-1702916-A1 DPP-IV inhibitors Santhera Pharmaceuticals (Schweiz) GmbH (CH) 2006-09-20 EP disclosed
EP-0422996-B1 Liquid crystal compound SHOWA SHELL SEKIYU (JP) 1995-04-12 EP disclosed
US-5328641-A Naphthalene ester derivatives with trifluoromethyl groups SHOWA SHELL SEKIYU KABUSHIKI KAISHA 1994-07-12 US disclosed
US-5207947-A Trifluoroalkyl diaryl triesters; antiferroelectricity; electrooptics SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1993-05-04 US disclosed
EP-0422996-A2 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-04-17 EP disclosed
US-4139381-A DIFFUSION TRANSFER, ANTIFOGGING AGENTS POLAROID CORPORATION (US) 1979-02-13 US disclosed
US-4088499-A METHYLENE GROUP CONTAINING POLYMERS EASTMAN KODAK COMPANY (US) 1978-05-09 US disclosed