Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17500452 | 0.84 | BRD4 (0.35) | VDRBRD4CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16749004 | 0.82 | F10 (0.33) | VDRBRD4CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17784003 | 0.82 | NPSR1 (0.38) | VDRCYP3A4CYP2C9CYP2C19NPSR1 | |
| SCHEMBL28352903 | 0.82 | HTT (0.33) | VDRCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13878962 | 0.80 | BRD4 (0.36) | BRD4PRMT1ALDH1A1SMN1; SMN2CES2 | |
| SCHEMBL663885 | 0.80 | BRD4 (0.38) | BRD4PRMT1ALDH1A1SMN1; SMN2CES2 | |
| SCHEMBL12549788 | 0.80 | BRD4 (0.38) | BRD4PRMT1ALDH1A1SMN1; SMN2CES2 | |
| SCHEMBL516378 | 0.80 | BRD4 (0.38) | BRD4PRMT1ALDH1A1SMN1; SMN2CES2 | |
| SCHEMBL23453503 | 0.78 | CYP2D6 (0.50) | CYP3A4CYP2D6CYP2C9CYP2C19HTT | |
| SCHEMBL17869205 | 0.78 | FFAR3 (0.46) | VDRCYP2C19SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348363-A1 | COMPOUNDS AND THEIR USE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348363-A1 | COMPOUNDS AND THEIR USE | RXFP1, RXFP3, RXFP2 | VDR 731/4885BRD4 2893/4885PRMT1 518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.