Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720182 | 0.92 | KMT2A (0.42) | KMT2ANPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL2669827 | 0.91 | KMT2A (0.42) | KMT2ANPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL3398050 | 0.89 | KMT2A (0.41) | KMT2ANPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL719521 | 0.83 | KMT2A (0.37) | KMT2ANPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL9070787 | 0.83 | KMT2A (0.46) | KMT2ANPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL718234 | 0.82 | NPC1 (0.45) | KMT2ANPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL717989 | 0.82 | KMT2A (0.43) | KMT2ANPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL718793 | 0.80 | KMT2A (0.42) | KMT2ANPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL720030 | 0.80 | KMT2A (0.43) | KMT2ANPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL720118 | 0.79 | KMT2A (0.43) | KMT2ANPC1RAB9AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |