Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.66 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.55 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30659854 | 1.00 | CRBN (0.66) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL24491253 | 0.85 | CRBN (0.66) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL25567227 | 0.85 | CRBN (0.66) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL20128680 | 0.85 | CRBN (0.66) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL24890982 | 0.85 | CRBN (0.66) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL21946811 | 0.85 | CRBN (0.67) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL31731776 | 0.84 | CRBN (0.62) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL21946768 | 0.83 | CRBN (0.63) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL31731804 | 0.83 | CRBN (0.63) | CRBNDDB1IKZF3BRD4 | |
| SCHEMBL23485053 | 0.82 | CRBN (0.62) | CRBNDDB1IKZF3BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226950-A1 | PEPTIDOMIMETIC STAT PROTEIN DEGRADER, COMPOSITION AND USE THEREOF | 杭州和正医药有限公司 | 2023-11-30 | — | — | WO | disclosed |
| CN-117126231-A | Peptoid STAT protein degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-11-28 | — | — | CN | disclosed |