Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12021702 | 0.80 | GCK (0.69) | GCKKCNH2 | |
| SCHEMBL2669971 | 0.80 | GCK (0.71) | GCKKCNH2 | |
| SCHEMBL9982925 | 0.80 | GCK (0.71) | GCKKCNH2 | |
| SCHEMBL3602195 | 0.79 | GCK (1.00) | GCKKCNH2 | |
| SCHEMBL3596787 | 0.78 | GCK (0.78) | GCKKCNH2 | |
| SCHEMBL13255097 | 0.77 | GCK (0.80) | GCKKCNH2 | |
| SCHEMBL3605901 | 0.77 | GCK (0.80) | GCKKCNH2 | |
| SCHEMBL13282946 | 0.76 | GCK (0.78) | GCKKCNH2 | |
| SCHEMBL2662465 | 0.76 | GCK (0.77) | GCKKCNH2 | |
| SCHEMBL2669849 | 0.76 | GCK (0.71) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009023718-A2 | NOVEL ACTIVATORS OF GLUCOKINASE | METABASIS THERAPEUTICS, INC. (US) | 2009-02-19 | — | — | WO | disclosed |