Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 9/20 | 0.43 |
| ▸ | BRAF | P15056 | 10/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936477 | 0.96 | GSK3A (0.46) | GSK3ABRAFMAPK14SRCSYK | |
| SCHEMBL2671344 | 0.87 | GSK3A (0.43) | GSK3ABRAFMAPK14SRCSYK | |
| SCHEMBL1936510 | 0.85 | MAPK14 (0.47) | GSK3ABRAFMAPK14SRCSYK | |
| SCHEMBL15062875 | 0.85 | GSK3A (0.42) | GSK3ABRAFMAPK14SRCSYK | |
| SCHEMBL1935998 | 0.84 | GSK3A (0.49) | GSK3ABRAFMAPK14SRCSYK | |
| SCHEMBL2671405 | 0.84 | MAPK14 (0.47) | GSK3ABRAFMAPK14SRCSYK | |
| SCHEMBL2670994 | 0.83 | MAPK14 (0.38) | GSK3ABRAFMAPK14SRCSYK | |
| SCHEMBL1936877 | 0.81 | MAPK14 (0.49) | GSK3ABRAFMAPK14SRCSYK | |
| SCHEMBL1936512 | 0.80 | MAPK14 (0.47) | GSK3ABRAFMAPK14SRCSYK | |
| SCHEMBL1935811 | 0.79 | MAPK14 (0.47) | GSK3ABRAFMAPK14SRCSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108572-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108572-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | HRH2, HRH1, HRH4 | GSK3A 1638/4885BRAF 3298/4885MAPK14 2338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.