Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 10/20 | 0.94 |
| ▸ | TGFBR1 | P36897 | 8/20 | 0.69 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.69 |
| ▸ | THRB | P10828 | 5/20 | 0.69 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.67 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.67 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29513182 | 1.00 | CSNK1D (0.94) | CSNK1DTGFBR1MAPK14THRBCSNK1A1 | |
| SCHEMBL26720722 | 0.97 | CSNK1D (1.00) | CSNK1DTGFBR1MAPK14THRBCSNK1A1 | |
| SCHEMBL29513204 | 0.97 | CSNK1D (1.00) | CSNK1DTGFBR1MAPK14THRBCSNK1A1 | |
| SCHEMBL26720635 | 0.88 | CSNK1D (0.74) | CSNK1DTGFBR1MAPK14THRBCSNK1A1 | |
| SCHEMBL29513377 | 0.88 | CSNK1D (0.74) | CSNK1DTGFBR1MAPK14THRBCSNK1A1 | |
| SCHEMBL26731813 | 0.86 | CSNK1D (1.00) | CSNK1DTGFBR1MAPK14THRBCSNK1A1 | |
| SCHEMBL29513383 | 0.86 | CSNK1D (1.00) | CSNK1DTGFBR1MAPK14THRBCSNK1A1 | |
| SCHEMBL26720639 | 0.86 | CSNK1D (0.75) | CSNK1DTGFBR1MAPK14THRBCSNK1A1 | |
| SCHEMBL29513136 | 0.86 | CSNK1D (0.75) | CSNK1DTGFBR1MAPK14THRBCSNK1A1 | |
| SCHEMBL29513335 | 0.85 | CSNK1D (0.69) | CSNK1DTGFBR1MAPK14THRBCSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116171280-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-05-26 | — | — | CN | claimed |
| US-20230339970-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
| US-20230339970-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339970-A1 | CASEIN KINASE 1 DELTA MODULATORS | CSNK1D, CSNK1A1, CSNK1G1 | CSNK1D 1/4885TGFBR1 2372/4885MAPK14 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.