Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 6/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10498354 | 1.00 | HTT (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10498297 | 1.00 | HTT (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10498169 | 1.00 | HTT (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10498312 | 1.00 | HTT (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10497843 | 1.00 | HTT (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10499225 | 1.00 | HTT (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL25466519 | 0.98 | HTT (0.46) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL12354888 | 0.98 | HTT (0.46) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL18512660 | 0.98 | HTT (0.46) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL2769016 | 0.98 | HTT (0.46) | HTTMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215823-A1 | MEASUREMENT OF PERMEATION OF SMALL MOLECULES INTO GRAM NEGATIVE BACTERIA | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2023-11-09 | — | — | WO | disclosed |