SCHEMBL26743545

SCHEMBL26743545

c1ccc(-c2cccc(-c3ccc4c(c3)c3c5ccccc5ccc3n4-c3nc(-c4ccccc4)nc4c3sc3ccc5ccccc5c34)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 2/20 0.34
PRKCI P41743 2/20 0.34
PIK3CA P42336 1/20 0.33
CYP1A1 P04798 1/20 0.32
CYP1B1 Q16678 1/20 0.32
PIM1 P11309 2/20 0.32
PIM2 Q9P1W9 2/20 0.32
PIM3 Q86V86 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26743507 0.92 PRKCI (0.33) LIMK1PRKCIPIK3CACYP1A1CYP1B1
SCHEMBL26743506 0.91 PIK3CA (0.37) LIMK1PRKCIPIK3CACYP1A1CYP1B1
SCHEMBL26743505 0.89 PIK3CA (0.38) PRKCIPIK3CACYP1A1CYP1B1
SCHEMBL18688010 0.85 PRKCI (0.31) PRKCI
SCHEMBL19257314 0.80 PRKCI (0.31) PRKCI
SCHEMBL26743456 0.80 PIK3CA (0.32) PRKCIPIK3CA
SCHEMBL17030425 0.80 PIK3CA (0.40) LIMK1PRKCIPIK3CAPIM1PIM2
SCHEMBL18853025 0.80 LIMK1 (0.38) LIMK1PIK3CACYP1A1CYP1B1PIM1
SCHEMBL26743330 0.79 PIK3CA (0.39) PRKCIPIK3CACYP1A1CYP1B1
SCHEMBL21134528 0.79 LIMK1 (0.32) LIMK1PIK3CAPIM1PIM2PIM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4265617-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT Materials Co., Ltd. (KR) 2023-10-25 EP disclosed