Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2676457 | 1.00 | CNR2 (0.49) | CNR2P2RX7TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL283367 | 0.84 | CNR2 (0.60) | CNR2 | |
| SCHEMBL2814455 | 0.80 | CNR2 (0.51) | CNR2POLBMAPK14 | |
| SCHEMBL283342 | 0.80 | CNR2 (0.51) | CNR2POLBMAPK14 | |
| SCHEMBL478443 | 0.78 | CNR2 (0.59) | CNR2 | |
| SCHEMBL2812699 | 0.77 | CNR2 (0.50) | CNR2KDM4EALDH1A1GAA | |
| SCHEMBL2815371 | 0.77 | CNR2 (0.50) | CNR2KDM4EALDH1A1GAA | |
| SCHEMBL2813991 | 0.71 | CNR2 (0.46) | CNR2KDM4EGAAKMT2AMEN1 | |
| SCHEMBL3388010 | 0.70 | CNR2 (0.65) | CNR2CNR1 | |
| SCHEMBL3388016 | 0.70 | CNR2 (0.65) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331516-B1 | IMINE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LAB (US) | 2013-03-13 | — | — | EP | disclosed |
| US-8173687-B2 | Compounds as cannabinoid receptor ligands | ABBOTT LABORATORIES (US) | 2012-05-08 | — | — | US | disclosed |
| CN-102123993-A | Imine derivatives as cannabinoid receptor ligands | ABBOTT LAB | 2011-07-13 | — | — | CN | disclosed |
| US-20100041720-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041720-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, NPY1R | CNR2 2/4885P2RX7 99/4885TAS1R3 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.