Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 17/20 | 0.85 |
| ▸ | PDE6C | P51160 | 2/20 | 0.85 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.73 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.71 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | PDE1A | P54750 | 1/20 | 0.70 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.70 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961638 | 0.94 | PDE5A (0.83) | PDE5APDE6CHDAC6HDAC1HDAC2 | |
| SCHEMBL31155653 | 0.93 | PDE5A (0.82) | PDE5APDE6CHDAC6HDAC1HDAC2 | |
| SCHEMBL25013451 | 0.93 | PDE5A (0.82) | PDE5APDE6CHDAC6HDAC1HDAC2 | |
| SCHEMBL7960838 | 0.92 | PDE5A (0.86) | PDE5APDE6CHDAC6HDAC1HDAC2 | |
| SCHEMBL7961020 | 0.92 | PDE5A (1.00) | PDE5APDE6CHDAC6HDAC1HDAC2 | |
| SCHEMBL18714952 | 0.91 | PDE5A (0.85) | PDE5APDE6CHDAC6HDAC1HDAC2 | |
| SCHEMBL15996104 | 0.90 | PDE5A (0.83) | PDE5APDE6CHDAC6HDAC1HDAC2 | |
| SCHEMBL16003752 | 0.89 | PDE5A (0.87) | PDE5APDE6CHDAC6HDAC1HDAC2 | |
| SCHEMBL29357402 | 0.88 | PDE5A (0.85) | PDE5APDE6CHDAC6HDAC1HDAC2 | |
| SCHEMBL25013469 | 0.88 | PDE5A (0.85) | PDE5APDE6CHDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372351-A1 | TREATMENT OF ERECTILE DYSFUNCTION AND OTHER INDICATIONS | STRATEGIC SCIENCE & TECHNOLOGIES, LLC (US) | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230372351-A1 | TREATMENT OF ERECTILE DYSFUNCTION AND OTHER INDICATIONS | PDE5A, PDE3A, PDE12 | PDE5A 1/4885PDE6C 21/4885HDAC6 1886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.