Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.48 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.42 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.42 |
| ▸ | L3MBTL4 | Q8NA19 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | PHF20 | Q9BVI0 | 1/20 | 0.42 |
| ▸ | MORF4L1 | Q9UBU8 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26773485 | 1.00 | HRH3 (0.49) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL26773486 | 1.00 | HRH3 (0.49) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL26773556 | 0.89 | HRH3 (0.44) | HRH3L3MBTL3L3MBTL1LRRK2 | |
| SCHEMBL26773472 | 0.89 | PTK2 (0.42) | HRH3BTK | |
| SCHEMBL26773388 | 0.89 | TYK2 (0.44) | HRH3BTK | |
| SCHEMBL26773473 | 0.89 | PTK2 (0.42) | HRH3BTK | |
| SCHEMBL26773301 | 0.89 | CCNT1 (0.42) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL26773475 | 0.89 | PTK2 (0.42) | HRH3BTK | |
| SCHEMBL26773471 | 0.89 | TYK2 (0.44) | HRH3BTK | |
| SCHEMBL26773320 | 0.88 | MAPT (0.47) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192464-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | Origenis GmbH (DE) | 2023-06-14 | — | — | EP | claimed |
| US-20230373985-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | ORIGENIS GMBH (DE) | 2023-11-23 | — | — | US | disclosed |
| US-20230373985-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | ORIGENIS GMBH (DE) | 2023-11-23 | — | — | US | disclosed |
| US-20230373985-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | ORIGENIS GMBH (DE) | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373985-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | TYK2, MAPKAPK2, MAP3K20 | HRH3 912/4885L3MBTL3 2148/4885L3MBTL1 2031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.