⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13266212 | 0.73 | — | — | |
| SCHEMBL22142906 | 0.73 | — | — | |
| SCHEMBL6518837 | 0.73 | — | — | |
| SCHEMBL18903786 | 0.73 | — | — | |
| SCHEMBL17080725 | 0.73 | — | — | |
| SCHEMBL17787722 | 0.71 | — | — | |
| SCHEMBL13357527 | 0.71 | — | — | |
| SCHEMBL24191640 | 0.71 | — | — | |
| SCHEMBL19021882 | 0.71 | — | — | |
| SCHEMBL22780920 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365592-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. | 2023-11-16 | — | — | US | disclosed |