Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Isosorbide Mononitrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.78 |
| ▸ | BCHE | P06276 | 6/20 | 0.58 |
| ▸ | GSR | P00390 | 7/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isosorbide Mononitrate SCHEMBL8893635 | 1.00 | MAPT (1.00) | MAPTALDH1A1BCHEGSRCA2 | |
| Isosorbide Mononitrate SCHEMBL12238510 | 1.00 | MAPT (1.00) | MAPTALDH1A1BCHEGSRCA2 | |
| Isosorbide Mononitrate SCHEMBL8894719 | 1.00 | MAPT (1.00) | MAPTALDH1A1BCHEGSRCA2 | |
| Isosorbide Mononitrate SCHEMBL3056251 | 1.00 | MAPT (1.00) | MAPTALDH1A1BCHEGSRCA2 | |
| Isosorbide Mononitrate SCHEMBL616518 | 1.00 | MAPT (1.00) | MAPTALDH1A1BCHEGSRCA2 | |
| Isosorbide Mononitrate SCHEMBL5482432 | 1.00 | MAPT (1.00) | MAPTALDH1A1BCHEGSRCA2 | |
| Isosorbide Mononitrate SCHEMBL23906861 | 1.00 | MAPT (1.00) | MAPTALDH1A1BCHEGSRCA2 | |
| Isosorbide Mononitrate SCHEMBL12787633 | 1.00 | MAPT (1.00) | MAPTALDH1A1BCHEGSRCA2 | |
| Isosorbide Mononitrate SCHEMBL26782 | 1.00 | MAPT (1.00) | MAPTALDH1A1BCHEGSRCA2 | |
| Isosorbide Mononitrate SCHEMBL22067709 | 1.00 | MAPT (1.00) | MAPTALDH1A1BCHEGSRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 37458 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122091781-A | Electrode lug structure design and preparation method of cylindrical battery | — | 2026-05-26 | — | — | CN | claimed |
| US-20260142350-A1 | SECONDARY BATTERY AND METHOD OF MANUFACTURING SECONDARY BATTERY | SAMSUNG SDI CO LTD (KR) | 2026-05-21 | — | — | US | claimed |
| WO-2026102976-A1 | BATTERY CELL PROTECTION CIRCUIT, MULTI-TAB BATTERY CELL, BATTERY AND ELECTRONIC DEVICE | 惠州锂威新能源科技有限公司 | 2026-05-21 | — | — | WO | claimed |
| CN-224264244-U | Multipolar ear cell structure and battery | 深圳市比克动力电池有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122070280-A | FPR1 modulators, compositions comprising the modulators, and methods of use thereof | 百放开曼有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122065790-A | Method and system for processing multi-tab data of electronic form | 蒲惠智造科技股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| EP-4742435-A2 | SECONDARY BATTERY HAVING SYMMETRIC MULTI-TABS | SAMSUNG SDI CO., LTD. (KR) | 2026-05-13 | — | — | EP | claimed |
| EP-3588618-B1 | SECONDARY BATTERY HAVING SYMMETRIC MULTI-TABS | SAMSUNG SDI CO LTD (KR) | 2026-05-06 | — | — | EP | claimed |
| EP-4736841-A1 | A MUCOADHESIVE LAYER FOR BUCCAL ADMINISTRATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT | IQ medical GmbH (DE) | 2026-05-06 | — | — | EP | claimed |
| WO-2026090251-A1 | METHODS FOR IMPROVING TREATMENT OUTCOMES IN PATIENTS UNDERGOING ULTRAFILTRATION | PROLETARIAT THERAPEUTICS, INC. (US) | 2026-04-30 | — | — | WO | claimed |
| EP-0077036-B1 | BINDING AGENT COMPOSITIONS | UNION CARBIDE CORPORATION (US) | 1986-01-08 | — | — | EP | claimed |
| EP-0078299-B1 | METHOD AND DEVICE FOR DETERMINING THE NITROGEN CONTENT IN AMMONIUM NITROGEN CONTAINING MATERIALS | ENGLUND, Claes Anders (SE) | 1985-10-30 | — | — | EP | claimed |
| EP-0150063-A2 | Therapeutic and/or preventive ophthalmic solution for intraocular hypertension and glaucoma | Eisai Co., Ltd. (JP) | 1985-07-31 | — | — | EP | claimed |
| EP-0143507-A1 | A method for the preparation of isosorbide-5-nitrate and sodium isosorbide-5-nitrate hydrate as a precursor thereof | TOSHIN CHEMICAL CO., Ltd. (JP) | 1985-06-05 | — | — | EP | claimed |
| EP-0046912-B1 | CYANIDE GOLD-BATHS AND PROCESS FOR THE GALVANIC DEPOSITION OF GOLD-DISPERSION COATINGS THAT CONTAIN SOLID LUBRICANT, AND ITS APPLICATION | SIEMENS AKTIENGESELLSCHAFT (DE) | 1984-07-11 | — | — | EP | claimed |
| EP-0104877-A2 | Organic nitrate drug mixtures resistant to detonation by fire | ICI AMERICAS INC. (US) | 1984-04-04 | — | — | EP | claimed |
| US-4431830-A | Process for the preparation of isosorbide-5-nitrate | CASSELLA AKTIENGESELLSCHAFT (DE) | 1984-02-14 | — | — | US | claimed |
| US-4371703-A | Process for the production of isosorbide-5-nitrate | HEINRICH MACK NACHF. CHEM-PARM. FABRIK (DE) | 1983-02-01 | — | — | US | claimed |
| US-4297286-A | Process for selectively producing isosorbide-5-nitrate | SANOL SCHWARZ-MONHEIN GMBH (DE) | 1981-10-27 | — | — | US | claimed |
| US-4065488-A | Process for preparing 1,4:3,6-dianhydro-D-glucitol 2-nitrate | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-12-27 | — | — | US | claimed |