Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25319921 | 0.93 | TIPARP (0.33) | TIPARPDGAT1 | |
| SCHEMBL25323199 | 0.90 | TIPARP (0.42) | TIPARPDGAT1 | |
| SCHEMBL25323197 | 0.90 | TIPARP (0.42) | TIPARPDGAT1 | |
| SCHEMBL26782300 | 0.88 | TIPARP (0.43) | TIPARPDGAT1 | |
| SCHEMBL31058417 | 0.84 | TIPARP (0.41) | TIPARPDGAT1 | |
| SCHEMBL25322516 | 0.81 | TIPARP (0.37) | TIPARPDGAT1 | |
| SCHEMBL30550874 | 0.81 | TIPARP (0.37) | TIPARPDGAT1 | |
| SCHEMBL25322652 | 0.80 | TIPARP (0.43) | TIPARPDGAT1 | |
| SCHEMBL25320149 | 0.80 | TIPARP (0.45) | TIPARPDGAT1 | |
| SCHEMBL25320156 | 0.80 | TIPARP (0.45) | TIPARPDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365529-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. | 2023-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365529-A1 | PARP7 INHIBITORS | PARP1, PARP11, PARP2 | TIPARP 491/4885DGAT1 2812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.