Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20628351 | 0.91 | MAPK13 (0.37) | MAPTSMN1; SMN2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL13699061 | 0.91 | MAPT (0.40) | MAPTSMN1; SMN2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL12187066 | 0.89 | MAPT (0.39) | MAPTSMN1; SMN2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL18627800 | 0.89 | AKT1 (0.39) | MAPTALDH1A1HPGDL3MBTL1NPC1 | |
| SCHEMBL12956088 | 0.86 | MAPT (0.36) | MAPTSMN1; SMN2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL21316766 | 0.86 | MAPT (0.37) | MAPTSMN1; SMN2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL18789928 | 0.81 | MAPT (0.47) | MAPTSMN1; SMN2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL24693324 | 0.81 | — | — | |
| SCHEMBL19529183 | 0.81 | — | — | |
| SCHEMBL15684691 | 0.80 | TSHR (0.44) | SMN1; SMN2ALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11813338-B2 | Diagnosing and treating cancer | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2023-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11813338-B2 | Diagnosing and treating cancer | CHKA, CHKB, CILK1 | MAPT 714/4885SMN1; SMN2 2709/4885ALDH1A1 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.