Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | FABP7 | O15540 | 1/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5954294 | 1.00 | EPHX1 (0.48) | EPHX1CES2CES1FABP7FABP5 | |
| SCHEMBL27680260 | 1.00 | EPHX1 (0.48) | EPHX1CES2CES1FABP7FABP5 | |
| SCHEMBL26666920 | 1.00 | EPHX1 (0.48) | EPHX1CES2CES1FABP7FABP5 | |
| SCHEMBL5953668 | 1.00 | EPHX1 (0.48) | EPHX1CES2CES1FABP7FABP5 | |
| SCHEMBL170007 | 1.00 | EPHX1 (0.48) | EPHX1CES2CES1FABP7FABP5 | |
| SCHEMBL17061159 | 1.00 | EPHX1 (0.48) | EPHX1CES2CES1FABP7FABP5 | |
| SCHEMBL24595803 | 1.00 | EPHX1 (0.48) | EPHX1CES2CES1FABP7FABP5 | |
| SCHEMBL11038809 | 1.00 | EPHX1 (0.48) | EPHX1CES2CES1FABP7FABP5 | |
| SCHEMBL17061158 | 1.00 | EPHX1 (0.48) | EPHX1CES2CES1FABP7FABP5 | |
| SCHEMBL7876271 | 1.00 | EPHX1 (0.48) | EPHX1CES2CES1FABP7FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557519-B1 | PROCESS FOR PREPARING SULFONAMIDE DERIVATIVE OF NORBORNANE | SHIONOGI & CO (JP) | 1997-06-04 | — | — | EP | claimed |
| EP-2112200-B1 | RESIN ADDITIVE MASTER BATCH | ADEKA CORP (JP) | 2013-03-27 | — | — | EP | disclosed |
| CN-101605848-B | Resin Additive Masterbatch | ADEKA CORP JP | 2012-06-27 | — | — | CN | disclosed |
| US-8173735-B2 | Resin additive master batch | ADEKA CORPORATION (JP) | 2012-05-08 | — | — | US | disclosed |
| US-20100093899-A1 | RESIN ADDITIVE MASTER BATCH | ADEKA CORPORATION (JP) | 2010-04-15 | — | — | US | disclosed |
| CN-101605848-A | Resin Additive Masterbatch | ADEKA CORP (JP) | 2009-12-16 | — | — | CN | disclosed |
| EP-2112200-A1 | RESIN ADDITIVE MASTER BATCH | Adeka Corporation (JP) | 2009-10-28 | — | — | EP | disclosed |
| EP-0557519-B1 | PROCESS FOR PREPARING SULFONAMIDE DERIVATIVE OF NORBORNANE | SHIONOGI & CO (JP) | 1997-06-04 | — | — | EP | disclosed |
| US-5525506-A | Process for production of avermectins and cultures therefor | PFIZER INC. (US) | 1996-06-11 | — | — | US | disclosed |
| EP-0557519-A1 | PROCESS FOR PREPARING SULFONAMIDE DERIVATIVE OF NORBORNANE | SHIONOGI & CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-5238848-A | Cultures for production of avermectins | PFIZER INC (US) | 1993-08-24 | — | — | US | disclosed |
| US-5124462-A | PREPARATION OF NORBORNYL SULFONAMIDE DERIVATIVES | SHIONGI & CO., LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| US-5077278-A | Parasiticides | PFIZER INC. (US) | 1991-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093899-A1 | RESIN ADDITIVE MASTER BATCH | PCNA, RAD51, MRE11 | EPHX1 4367/4885CES2 4111/4885CES1 4416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.