Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 19/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2676941 | 0.97 | EPHX2 (0.64) | EPHX2CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL2676942 | 0.97 | EPHX2 (0.64) | EPHX2CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL2678080 | 0.97 | EPHX2 (0.64) | EPHX2CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL2678425 | 0.93 | EPHX2 (0.52) | EPHX2CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL2677015 | 0.93 | EPHX2 (0.52) | EPHX2CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL2677018 | 0.93 | EPHX2 (0.52) | EPHX2CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL2676508 | 0.87 | EPHX2 (0.79) | EPHX2CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL2677761 | 0.87 | EPHX2 (0.79) | EPHX2CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL2677763 | 0.87 | EPHX2 (0.79) | EPHX2CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL5036623 | 0.87 | EPHX2 (0.65) | EPHX2CYP2C9CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173805-B2 | sEH inhibitors and their use | GlaxoSmithKline, LLC (US) | 2012-05-08 | — | — | US | claimed |