Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 17/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26791863 | 0.87 | HRH3 (0.38) | ACACBHRH4HRH3 | |
| SCHEMBL26850081 | 0.87 | ACACB (0.35) | ACACBKDM4ENPC1RAB9APANK3 | |
| SCHEMBL18714938 | 0.83 | HRH3 (0.39) | ACACBKDM4ENPC1RAB9AHRH4 | |
| SCHEMBL11996276 | 0.80 | ACACB (0.36) | ACACBKCNH2HRH4HRH3PANK3 | |
| SCHEMBL18782870 | 0.79 | ACACB (0.47) | ACACBPANK3 | |
| SCHEMBL19756416 | 0.79 | ACACB (0.41) | ACACBPANK3 | |
| SCHEMBL29308763 | 0.79 | ACACB (0.38) | ACACBKCNH2 | |
| SCHEMBL19756406 | 0.76 | SMO (0.35) | ACACBKDM4ENPC1RAB9A | |
| SCHEMBL26818713 | 0.76 | ACACB (0.34) | ACACBKCNH2HRH4HRH3PANK3 | |
| SCHEMBL26089355 | 0.76 | PTPN11 (0.41) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220134-A1 | PYRAZINE DERIVATIVES AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |