Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 15/20 | 0.64 |
| ▸ | BCR | P11274 | 15/20 | 0.64 |
| ▸ | KIT | P10721 | 8/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.55 |
| ▸ | EGFR | P00533 | 3/20 | 0.55 |
| ▸ | LCK | P06239 | 3/20 | 0.55 |
| ▸ | CSF1R | P07333 | 3/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.55 |
| ▸ | FYN | P06241 | 2/20 | 0.55 |
| ▸ | LYN | P07948 | 2/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.55 |
| ▸ | FGR | P09769 | 2/20 | 0.55 |
| ▸ | SRC | P12931 | 2/20 | 0.55 |
| ▸ | BRAF | P15056 | 2/20 | 0.55 |
| ▸ | NQO2 | P16083 | 2/20 | 0.55 |
| ▸ | EPHA8 | P29322 | 2/20 | 0.55 |
| ▸ | ABL2 | P42684 | 2/20 | 0.55 |
| ▸ | FRK | P42685 | 2/20 | 0.55 |
| ▸ | BLK | P51451 | 2/20 | 0.55 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10054806 | 1.00 | ABL1 (0.64) | ABL1BCRKITPDGFRAEGFR | |
| SCHEMBL2679249 | 0.94 | ABL1 (0.63) | ABL1BCRKITPDGFRAEGFR | |
| SCHEMBL10054795 | 0.94 | ABL1 (0.63) | ABL1BCRKITPDGFRAEGFR | |
| SCHEMBL2679905 | 0.92 | ABL1 (0.59) | ABL1BCRKITPDGFRAEGFR | |
| SCHEMBL10054804 | 0.92 | ABL1 (0.59) | ABL1BCRKITPDGFRAEGFR | |
| SCHEMBL10054798 | 0.91 | ABL1 (0.57) | ABL1BCRKITPDGFRAEGFR | |
| SCHEMBL2679280 | 0.91 | ABL1 (0.57) | ABL1BCRKITPDGFRAEGFR | |
| SCHEMBL10054809 | 0.91 | ABL1 (0.61) | ABL1BCRKITPDGFRAEGFR | |
| SCHEMBL2678924 | 0.90 | ABL1 (0.59) | ABL1BCRKITPDGFRAEGFR | |
| SCHEMBL10054808 | 0.90 | ABL1 (0.59) | ABL1BCRKITPDGFRAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426446-B2 | Acrylamide derivative and use thereof in manufacture of medicament | BEIJING SHIQIAO BIOPHARM CO. LTD. (CN) | 2013-04-23 | — | — | US | claimed |
| US-20120116075-A1 | Acrylamide Derivative And Use Thereof In Manufacture Of Medicament | BEIJING JIASHILIANBO PHARM SCI & TECH CO. LTD | 2012-05-10 | — | — | US | claimed |
| US-8426446-B2 | Acrylamide derivative and use thereof in manufacture of medicament | BEIJING SHIQIAO BIOPHARM CO. LTD. (CN) | 2013-04-23 | — | — | US | disclosed |
| US-20120116075-A1 | Acrylamide Derivative And Use Thereof In Manufacture Of Medicament | BEIJING JIASHILIANBO PHARM SCI & TECH CO. LTD | 2012-05-10 | — | — | US | disclosed |
| CN-102421754-A | Acrylamide derivative and use thereof in manufacture of medicament | BEIJING JIASHILIANBO PHARM SCI & TECH CO LTD | 2012-04-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120116075-A1 | Acrylamide Derivative And Use Thereof In Manufacture Of Medicament | ABL1, ABL2, BCR | ABL1 1/4885BCR 3/4885KIT 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.