Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CTSK | P43235 | 10/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26748563 | 1.00 | CA1 (0.56) | CA1CA2CA7CTSKAPLNR | |
| SCHEMBL25467816 | 0.89 | CA1 (0.57) | CA1CA2CA7CTSKAPLNR | |
| SCHEMBL30669135 | 0.89 | CA1 (0.57) | CA1CA2CA7CTSKAPLNR | |
| SCHEMBL25467746 | 0.89 | CA1 (0.57) | CA1CA2CA7CTSKAPLNR | |
| SCHEMBL11123814 | 0.87 | CA1 (0.51) | CA1CA2CA7CTSKAPLNR | |
| SCHEMBL29832536 | 0.85 | CA1 (0.53) | CA1CA2CA7CTSKAPLNR | |
| SCHEMBL14851200 | 0.85 | CA1 (0.53) | CA1CA2CA7CTSKAPLNR | |
| SCHEMBL1414602 | 0.85 | CA1 (0.71) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL1809665 | 0.85 | CA1 (0.71) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL1134642 | 0.85 | CA1 (0.71) | CA1CA2CA7CTSKCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023212231-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-11-02 | — | — | WO | disclosed |