Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 8/20 | 0.40 |
| ▸ | GSTM2 | P28161 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26797894 | 0.88 | GSTP1 (0.40) | GSTP1GSTM2LMNASMN1; SMN2MAPT | |
| SCHEMBL26797772 | 0.85 | GSTP1 (0.57) | GSTP1GSTM2 | |
| SCHEMBL30599546 | 0.85 | GSTP1 (0.57) | GSTP1GSTM2 | |
| SCHEMBL26797778 | 0.74 | GSTP1 (0.70) | GSTP1GSTM2 | |
| SCHEMBL26797780 | 0.74 | GSTP1 (0.57) | GSTP1GSTM2 | |
| SCHEMBL26797775 | 0.74 | GSTP1 (0.57) | GSTP1GSTM2 | |
| SCHEMBL30599559 | 0.72 | GSTP1 (0.57) | GSTP1GSTM2 | |
| SCHEMBL26797771 | 0.72 | GSTP1 (0.57) | GSTP1GSTM2 | |
| SCHEMBL2098480 | 0.68 | HPGD (0.50) | LMNASMN1; SMN2MAPTALDH1A1TSHR | |
| SCHEMBL26463526 | 0.67 | HPGD (0.52) | LMNASMN1; SMN2MAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365516-A1 | COMPOUNDS FOR CANCER THERAPY AND IMAGING | WASHINGTON UNIVERSITY | 2023-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365516-A1 | COMPOUNDS FOR CANCER THERAPY AND IMAGING | MKI67, VHL, TP53 | GSTP1 864/4885GSTM2 1336/4885LMNA 2033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.