SCHEMBL2679808

SCHEMBL2679808

CCOC(=O)Cc1c(C(=O)N2CCC(c3ccccc3F)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2063425 0.89 CNR1 (1.00) CNR1
SCHEMBL2063748 0.87 CNR1 (0.81) CNR1
SCHEMBL2679080 0.86 CNR1 (0.80) CNR1
SCHEMBL10083631 0.86 CNR1 (0.85) CNR1
SCHEMBL3827240 0.86 CNR1 (0.82) CNR1
SCHEMBL6123586 0.86 CNR1 (0.82) CNR1
SCHEMBL2678373 0.85 CNR1 (0.81) CNR1
SCHEMBL2677521 0.84 CNR1 (0.79) CNR1
SCHEMBL2063602 0.84 CNR1 (0.90) CNR1
SCHEMBL6124839 0.83 CNR1 (0.75) CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173680-B2 Cannabinoid receptor modulators 7TM PHARMA A/S (DK) 2012-05-08 US disclosed
US-8173680-B2 Cannabinoid receptor modulators 7TM PHARMA A/S (DK) 2012-05-08 US disclosed
US-8148404-B2 Modulators of CB1 receptors 7TM PHARMA A/S (DK) 2012-04-03 US disclosed
US-20100292273-A1 Cannabinoid Receptor Modulators 7TM PHARMA A/S (DK) 2010-11-18 US disclosed
US-20100292273-A1 Cannabinoid Receptor Modulators 7TM PHARMA A/S (DK) 2010-11-18 US disclosed
EP-2231615-A1 CANNABINOID RECEPTOR MODULATORS 7TM Pharma A/S (DK) 2010-09-29 EP disclosed
US-20100144701-A1 Modulators of CB1 Receptors 7TM PHARMA A/S (DK) 2010-06-10 US disclosed
WO-2009074782-A1 CANNABINOID RECEPTOR MODULATORS 7TM PHARMA A/S (DK) 2009-06-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292273-A1 Cannabinoid Receptor Modulators CNR1, CNR2, CBR1 CNR1 1/4885
US-20100144701-A1 Modulators of CB1 Receptors CNR1, CNR2, GPR6 CNR1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.