SCHEMBL26800644

SCHEMBL26800644

c1ccc([Si](c2ccccc2)(c2ccccc2)c2cccc(-c3nc(-c4nc(-n5c6ccccc6c6ccccc65)nc(-n5c6ccccc6c6ccccc65)n4)nc(-n4c5ccccc5c5ccccc54)n3)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ATM Q13315 2/20 0.35
ABCG2 Q9UNQ0 3/20 0.33
ABCB1 P08183 1/20 0.33
NR1I3 Q14994 4/20 0.32
CYP1A2 P05177 3/20 0.32
CYP3A4 P08684 3/20 0.32
CYP2C9 P11712 3/20 0.32
CYP2B6 P20813 2/20 0.32
AHR P35869 2/20 0.32
VDR P11473 1/20 0.32
MEN1 O00255 5/20 0.32
KMT2A Q03164 5/20 0.32
ALDH1A1 P00352 4/20 0.32
HPGD P15428 4/20 0.32
LMNA P02545 3/20 0.32
MAPT P10636 3/20 0.32
USP2 O75604 2/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26880735 1.00 KDM4E (0.35) KDM4EL3MBTL1ATMABCG2ABCB1
SCHEMBL26840017 0.99 ABCG2 (0.35) KDM4EL3MBTL1ATMABCG2ABCB1
SCHEMBL23622549 0.97 KDM4E (0.37) KDM4EL3MBTL1ATMABCG2ABCB1
SCHEMBL30846074 0.97 KDM4E (0.37) KDM4EL3MBTL1ATMABCG2ABCB1
SCHEMBL22038577 0.97 KDM4E (0.37) KDM4EL3MBTL1ATMABCG2ABCB1
SCHEMBL22038578 0.97 KDM4E (0.37) KDM4EL3MBTL1ATMABCG2ABCB1
SCHEMBL15490810 0.96 ABCG2 (0.36) KDM4EL3MBTL1ATMABCG2ABCB1
SCHEMBL30990193 0.96 ABCG2 (0.36) KDM4EL3MBTL1ATMABCG2ABCB1
SCHEMBL23268344 0.96 KDM4E (0.36) KDM4EL3MBTL1ATMABCG2ABCB1
SCHEMBL25449269 0.94 KDM4E (0.35) KDM4EL3MBTL1ATMABCG2ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230389421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-30 US disclosed
US-20230389421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-30 US disclosed
EP-4282863-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-11-29 EP disclosed