Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | GAPDH | P04406 | 2/20 | 0.47 |
| ▸ | HRAS | P01112 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26647552 | 0.91 | POLB (0.54) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL26647574 | 0.91 | POLB (0.54) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL10118029 | 0.83 | MEN1 (0.61) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL307724 | 0.83 | USP2 (0.61) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL308528 | 0.83 | MEN1 (0.61) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL12841594 | 0.81 | MEN1 (0.57) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL1536670 | 0.81 | MEN1 (0.57) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL10118025 | 0.79 | MEN1 (0.59) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL307747 | 0.79 | MEN1 (0.61) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL24487795 | 0.79 | MEN1 (0.61) | MEN1USP2POLBKMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220428-A1 | COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |