SCHEMBL26803753

SCHEMBL26803753

CNC(=O)C(CCCCNC(=O)CCOCCOCCNC(=O)CCOCCOCCNC(=O)CCCCCCCCCCCCCCC(=O)O)NC

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.52
▸ FOLH1 Q04609 5/20 0.44
▸ EPOR P19235 3/20 0.42
▸ EPHX2 P34913 3/20 0.41
▸ ADRA1A P35348 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19057811 1.00 GLP1R (0.52) GLP1RFOLH1EPOREPHX2ADRA1A
SCHEMBL26803757 0.92 GLP1R (0.65) GLP1RFOLH1
SCHEMBL19057808 0.92 GLP1R (0.65) GLP1RFOLH1
SCHEMBL19057810 0.91 GLP1R (0.57) GLP1REPHX2
SCHEMBL26803766 0.91 GLP1R (0.57) GLP1REPHX2
SCHEMBL11920365 0.91 GLP1R (0.57) GLP1RFOLH1EPOREPHX2
SCHEMBL11920370 0.91 GLP1R (0.57) GLP1RFOLH1EPOREPHX2
SCHEMBL14118023 0.91 GLP1R (0.57) GLP1RFOLH1EPOREPHX2
SCHEMBL11920369 0.91 GLP1R (0.57) GLP1RFOLH1EPOREPHX2
SCHEMBL23544197 0.90 GLP1R (0.50) GLP1RFOLH1EPOREPHX2ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230364194-A1 GLP-1R/GCGR Dual Target Agonist Polypeptide Derivative for Treatment of Hepatic Fibrosis Associated with Viral Hepatitis SHENZHEN TURIER BIOTECH CO., LTD. (CN) 2023-11-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230364194-A1 GLP-1R/GCGR Dual Target Agonist Polypeptide Derivative for Treatment of Hepatic Fibrosis Associated with Viral Hepatitis GLP1R, GCGR, GIPR GLP1R 1/4885FOLH1 513/4885EPOR 786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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