Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26656125 | 0.83 | AAK1 (0.60) | AAK1ALDH1A1TSHRADRB2ADRB1 | |
| SCHEMBL26804255 | 0.77 | AAK1 (0.41) | AAK1RAB9AHPGDPOLBMAPT | |
| SCHEMBL28269203 | 0.76 | MEN1 (0.44) | AAK1MAPTALDH1A1TSHRCHRM5 | |
| SCHEMBL25467872 | 0.75 | AAK1 (0.44) | AAK1RAB9AHPGDPOLBMAPT | |
| SCHEMBL1064740 | 0.74 | MEN1 (0.43) | AAK1MAPTALDH1A1TSHRCTSK | |
| SCHEMBL25319859 | 0.70 | AAK1 (0.61) | AAK1ALDH1A1CTSK | |
| SCHEMBL2652706 | 0.69 | AAK1 (0.60) | AAK1ALDH1A1CTSK | |
| SCHEMBL2652864 | 0.69 | AAK1 (0.60) | AAK1ALDH1A1CTSK | |
| SCHEMBL25383775 | 0.68 | AAK1 (0.52) | AAK1POLBMAPTALDH1A1TSHR | |
| SCHEMBL11130905 | 0.67 | AAK1 (0.51) | AAK1RAB9APOLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220439-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |