Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30256967 | 0.93 | TDP1 (0.64) | TDP1SMN1; SMN2ECE1SLC22A6GABRR1 | |
| SCHEMBL23170133 | 0.92 | TDP1 (0.58) | TDP1SMN1; SMN2ECE1GABRR1LMNA | |
| SCHEMBL22151 | 0.86 | TDP1 (1.00) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA | |
| SCHEMBL17517216 | 0.86 | TDP1 (1.00) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA | |
| SCHEMBL16925719 | 0.86 | TDP1 (1.00) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA | |
| SCHEMBL165643 | 0.86 | TDP1 (1.00) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA | |
| SCHEMBL8078228 | 0.83 | TDP1 (0.93) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA | |
| SCHEMBL269896 | 0.83 | TDP1 (0.93) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA | |
| SCHEMBL9678882 | 0.83 | TDP1 (0.93) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA | |
| SCHEMBL9355977 | 0.83 | TDP1 (0.93) | TDP1SMN1; SMN2SLC22A6GABRR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120114873-A1 | PROCESS OF PRODUCING AN OPTICAL FILM | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-05-10 | — | — | US | disclosed |