Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.52 |
| ▸ | AR | P10275 | 6/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24031399 | 0.93 | CRBN (0.54) | CRBNARDDB1BTK | |
| SCHEMBL26808846 | 0.92 | CRBN (0.54) | CRBNARDDB1BTK | |
| SCHEMBL26808203 | 0.91 | CRBN (0.54) | CRBNARDDB1BTK | |
| SCHEMBL25902566 | 0.88 | CRBN (0.63) | CRBNARDDB1BTK | |
| SCHEMBL25902388 | 0.88 | CRBN (0.63) | CRBNARDDB1BTK | |
| SCHEMBL26816783 | 0.87 | CRBN (0.46) | CRBNARDDB1BTKALDH1A1 | |
| SCHEMBL26815881 | 0.85 | CRBN (0.48) | CRBNARDDB1ALDH1A1TSHR | |
| SCHEMBL26815610 | 0.85 | CRBN (0.47) | CRBNARDDB1ALDH1A1TSHR | |
| SCHEMBL26815785 | 0.85 | CRBN (0.47) | CRBNARDDB1ALDH1A1TSHR | |
| SCHEMBL24031624 | 0.84 | CRBN (0.61) | CRBNARDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357249-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS WITH A TRICYCLIC CEREBLON LIGAND | UNIV MICHIGAN REGENTS (US) | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357249-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS WITH A TRICYCLIC CEREBLON LIGAND | AR, GPER1, CRBN | CRBN 3/4885AR 1/4885DDB1 662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.