Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16094459 | 0.76 | ADORA1 (0.39) | ADORA2AADORA1 | |
| SCHEMBL29439820 | 0.72 | CDK1 (0.34) | ADORA2AADORA1 | |
| SCHEMBL22715058 | 0.72 | CDK1 (0.34) | ADORA2AADORA1 | |
| SCHEMBL2611024 | 0.69 | HRH4 (0.34) | ADORA2AADORA1 | |
| SCHEMBL26833890 | 0.69 | — | — | |
| SCHEMBL12931233 | 0.68 | HRH4 (0.30) | — | |
| SCHEMBL2600738 | 0.66 | — | — | |
| SCHEMBL7770550 | 0.66 | HRH4 (0.44) | ADORA2AADORA1 | |
| SCHEMBL26833487 | 0.64 | — | — | |
| SCHEMBL2600734 | 0.64 | CHRM3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827634-B2 | Small molecule inhibitors of NF-kB inducing kinase | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827634-B2 | Small molecule inhibitors of NF-kB inducing kinase | NFKBIA, IKBKB, NFRKB | ADORA2A 4776/4885ADORA1 4711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.