SCHEMBL268435

SCHEMBL268435

O=Cc1cc(C(=O)O)c(C(=O)O)cc1C=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 7/20 0.39
ALDH1A1 P00352 5/20 0.39
ALOX15 P16050 1/20 0.39
CYP1A2 P05177 1/20 0.39
POLB P06746 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
CASP6 P55212 2/20 0.38
CTDSP1 Q9GZU7 2/20 0.38
NSD2 O96028 1/20 0.38
PKM P14618 1/20 0.38
APEX1 P27695 1/20 0.38
CASP3 P42574 1/20 0.38
RECQL P46063 1/20 0.38
UNG P13051 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
KDM4E B2RXH2 1/20 0.36
HTT P42858 1/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14526673 0.90 ERN1 (0.37) ERN1ALDH1A1ALOX15CYP1A2POLB
SCHEMBL7614681 0.90 ERN1 (0.37) ERN1ALDH1A1ALOX15CYP1A2POLB
SCHEMBL10111663 0.89 ERN1 (0.39) ERN1ALDH1A1ALOX15CYP1A2POLB
SCHEMBL18239280 0.84 KDM4E (0.42) ERN1ALDH1A1POLBL3MBTL1TDP1
SCHEMBL10111667 0.81 ERN1 (0.38) ERN1ALDH1A1ALOX15CYP1A2POLB
SCHEMBL13361993 0.80 ERN1 (0.35) ERN1ALDH1A1ALOX15POLBL3MBTL1
SCHEMBL13447588 0.80 ERN1 (0.35) ERN1ALDH1A1ALOX15POLBL3MBTL1
SCHEMBL3097655 0.79 ERN1 (0.46) ERN1ALDH1A1ALOX15TDP1RECQL
SCHEMBL14103810 0.79 SLC22A6 (0.39) ERN1ALDH1A1ALOX15CYP1A2POLB
SCHEMBL547605 0.79 CYP3A4 (0.35) ERN1ALDH1A1ALOX15CYP1A2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4376707-A DIALYSIS GAMBRO DIALYSATOREN G.M.B.H. & CO. K.G. (DE) 1983-03-15 US claimed
JP-62062423-A None JP disclosed
JP-6036966-A None JP disclosed
JP-4320493-A None JP disclosed
WO-2020130437-A1 POLYIMIDE PRECURSOR COMPOSITION, AND POLYIMIDE PRODUCTION METHOD AND POLYIMIDE FILM USING SAME 주식회사 엘지화학 2020-06-25 WO disclosed
EP-2259141-B1 PROCESS FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2016-11-23 EP disclosed
EP-1757984-B1 Photosensitive lithographic printing plate FUJIFILM CORP (JP) 2016-05-18 EP disclosed
EP-2088468-B1 Method of preparing lithographic printing plate and lithographic printing plate precursor FUJIFILM CORP (JP) 2016-05-18 EP disclosed
EP-1975708-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2015-04-22 EP disclosed
EP-2166410-B1 Method of preparing lithographic printing plate FUJIFILM CORP (JP) 2013-12-11 EP disclosed
EP-0625547-B1 Flame retardative polycarbonate resin composition IDEMITSU PETROCHEMICAL CO (JP) 1998-10-14 EP disclosed
EP-0866081-A1 GRAFTED POLYOLEFIN RESIN AND THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME KANEKA CORPORATION (JP) 1998-09-23 EP disclosed
US-5449710-A Blends with metal salts of perfluoroalkanesulfonic acid and organopolysiloxane with optional fillers to prevent dripping IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-09-12 US disclosed
EP-0625547-A1 Flame retardative polycarbonate resin composition IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1994-11-23 EP disclosed
JP-H0636966-A THIN FILM CAPACITOR KOGYO GIJIYUTSUIN KAGAKU GIJUTSU KENKYUSHO 1994-02-10 JP disclosed
JP-H04320493-A POLYFUNCTIONAL FUEL ADDITIVE MOBIL OIL CORP 1992-11-11 JP disclosed
JP-S6262423-A MAGNETIC RECORDING MEDIUM AND BASE FILM CANON INC 1987-03-19 JP disclosed
US-4376707-A DIALYSIS GAMBRO DIALYSATOREN G.M.B.H. & CO. K.G. (DE) 1983-03-15 US disclosed
US-4250007-A Photocurable acrylic phosphate esters of epoxidized polybutadiene UBE INDUSTRIES, LTD. (JP) 1981-02-10 US disclosed
JP-S06262423-A 0001-01-01 JP disclosed