Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24315713 | 0.80 | GBA1 (0.37) | GBA1 | |
| SCHEMBL26147481 | 0.80 | GBA1 (0.33) | GBA1 | |
| SCHEMBL14752147 | 0.77 | GBA1 (0.38) | GBA1MAPK1KDM4EALDH1A1 | |
| SCHEMBL26790067 | 0.75 | GBA1 (0.42) | GBA1 | |
| SCHEMBL26147484 | 0.75 | ELANE (0.31) | — | |
| SCHEMBL18820447 | 0.75 | MAPK1 (0.37) | GBA1MAPK1KDM4EALDH1A1 | |
| SCHEMBL18174952 | 0.75 | ATM (0.35) | — | |
| SCHEMBL27053499 | 0.74 | KDM1A (0.33) | — | |
| SCHEMBL22784412 | 0.71 | — | — | |
| SCHEMBL22784166 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220137-A1 | PYRAZINE DERIVATIVES AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |