SCHEMBL2685050

SCHEMBL2685050

C=CCCCCCC[SiH2]Cl

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
ABCC4 O15439 1/20 0.39
MAPT P10636 1/20 0.39
ALDH1A1 P00352 4/20 0.38
TRPA1 O75762 3/20 0.37
LPAR3 Q9UBY5 2/20 0.34
LMNA P02545 2/20 0.34
LPAR2 Q9HBW0 1/20 0.34
TDP1 Q9NUW8 2/20 0.31
USP2 O75604 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8379543 1.00
SCHEMBL6740325 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL28482887 1.00 TSHR (0.46) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL2686427 0.97
SCHEMBL29104335 0.89
SCHEMBL3481826 0.77
SCHEMBL3361113 0.77 TSHR (0.44) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL3366893 0.77 TSHR (0.44) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL2846645 0.76 TSHR (0.69) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL18187344 0.76 TSHR (0.69) TSHRABCC4MAPTALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102498117-A Organic Chlorosilane And Method For Preparing Same SAMSUNG FINE CHEMICALS CO LTD 2012-06-13 CN disclosed
US-20120114544-A1 ORGANIC CHLOROHYDROSILANE AND METHOD FOR PREPARING THEM SAMSUNG FINE CHEMICALS CO., LTD (KR) 2012-05-10 US disclosed
US-20070276091-A1 Organic insulating film composition and method of manufacturing organic insulating film having dual thickness using the same SAMSUNG ELECTRONICS CO., LTD. 2007-11-29 US disclosed
US-6670286-B1 Photopolymerization-based fabrication of chemical sensing films THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120114544-A1 ORGANIC CHLOROHYDROSILANE AND METHOD FOR PREPARING THEM PHPT1, SIK1, SIK2 TSHR 4386/4885ABCC4 3035/4885MAPT 3981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.