Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20331249 | 0.98 | EPHX2 (0.42) | EPHX2PPARAPLA2G4BHDAC1HDAC2 | |
| SCHEMBL22560600 | 0.89 | EPHX2 (0.43) | EPHX2PPARAPLA2G4BHDAC1HDAC2 | |
| SCHEMBL21421549 | 0.88 | EPHX2 (0.44) | EPHX2PPARAPLA2G4BHDAC1HDAC2 | |
| SCHEMBL21026312 | 0.86 | EPHX2 (0.43) | EPHX2PPARAPLA2G4BHDAC1HDAC2 | |
| SCHEMBL24654312 | 0.86 | EPHX2 (0.42) | EPHX2PPARAPLA2G4BHDAC1HDAC2 | |
| SCHEMBL20133429 | 0.85 | APP (0.46) | EPHX2PLA2G4BHDAC1HDAC2L3MBTL1 | |
| SCHEMBL20234304 | 0.85 | APP (0.46) | EPHX2PLA2G4BHDAC1HDAC2L3MBTL1 | |
| SCHEMBL21025836 | 0.84 | EPHX2 (0.40) | EPHX2PPARAPLA2G4BHDAC1HDAC2 | |
| SCHEMBL20372668 | 0.84 | EPHX2 (0.40) | EPHX2PPARAPLA2G4BHDAC1HDAC2 | |
| SCHEMBL20133424 | 0.84 | PLA2G4B (0.45) | PPARAPLA2G4BL3MBTL1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834460-B2 | Imide-based modulators of proteolysis and associated methods of use | YALE UNIVERSITY (US) | 2023-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11834460-B2 | Imide-based modulators of proteolysis and associated methods of use | CRBN, MDM2, UBE2N | EPHX2 2244/4885PPARA 4714/4885PLA2G4B 3020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.