⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL263253 | 0.97 | — | — | |
| SCHEMBL141561 | 0.78 | — | — | |
| SCHEMBL4410073 | 0.78 | — | — | |
| SCHEMBL27360028 | 0.78 | — | — | |
| SCHEMBL170773 | 0.75 | — | — | |
| SCHEMBL21746445 | 0.75 | — | — | |
| SCHEMBL18889780 | 0.75 | — | — | |
| SCHEMBL12052865 | 0.75 | — | — | |
| SCHEMBL6549124 | 0.75 | TP53 (0.39) | — | |
| SCHEMBL7049582 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3851436-B1 | NOVEL HETEROAROMATIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | KAKEN PHARMA CO LTD (JP) | 2024-06-12 | — | — | EP | claimed |
| EP-3630758-A1 | ERGOLINE DERIVATIVES FOR USE IN MEDICINE | Xoc Pharmaceuticals, Inc (US) | 2020-04-08 | — | — | EP | claimed |
| WO-2018223065-A1 | ERGOLINE DERIVATIVES FOR USE IN MEDICINE | Xoc Pharmaceuticals, Inc. (US) | 2018-12-06 | — | — | WO | claimed |
| US-8143408-B2 | N-(8-heteroaryltetrahydronaphtalene-2yl) or N-(5-heteroarylchromane-3-yl) carboxamide derivatives for the treatment of pain | ASTRAZENECA AB (SE) | 2012-03-27 | — | — | US | claimed |
| US-20100137322-A1 | NOVEL N-(8-HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N-(5-HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2010-06-03 | — | — | US | claimed |
| EP-2158198-A2 | NOVEL N- (8HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N- (5- HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2010-03-03 | — | — | EP | claimed |
| WO-2008130320-A2 | NOVEL N- (8-HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N- (5- HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | claimed |
| EP-3774711-B1 | CYCLOPROPYL RING OPENING BY ALPHA ALKYLATION OF AN ALDEHYDE WITH A POLYCYCLIC OLEFIN | FIRMENICH & CIE (CH) | 2025-03-05 | — | — | EP | disclosed |
| CN-118073648-A | Difluorophosphate compound, electrolyte, secondary battery and device | 蔚来电池科技(安徽)有限公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20230348438-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2023-11-02 | — | — | US | disclosed |
| EP-4262788-A1 | UREA OREXIN RECEPTOR AGONISTS | Merck Sharp & Dohme LLC (US) | 2023-10-25 | — | — | EP | disclosed |
| US-11754926-B2 | Method of forming resist pattern, resist composition and method of producing the same | TOKYO OHKA KOGYO CO., LTD. (JP) | 2023-09-12 | — | — | US | disclosed |
| US-20230127914-A1 | RESIST PATTERN FORMATION METHOD | TOKYO OHKA KOGYO CO., LTD. (JP) | 2023-04-27 | — | — | US | disclosed |
| EP-0094538-A2 | Fluor-containing 4,6-diamino-s-triazines, process and intermediates for their preparation, and their use as herbicides | BAYER AG (DE) | 1983-11-23 | — | — | EP | disclosed |
| US-4402732-A | Herbicidally active dihalogenated imidazolecarboxylic acid amides, compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1983-09-06 | — | — | US | disclosed |
| EP-0039813-B1 | FLUOR-CONTAINING AZOMETHINES, PREPARATION THEREOF AND USE THEREOF AS INTERMEDIATES | BAYER AG (DE) | 1983-07-20 | — | — | EP | disclosed |
| EP-0073974-A2 | 4,6-Diamino-s-triazines containing fluor, process and intermediates for their preparation and their use as herbicides | BAYER AG (DE) | 1983-03-16 | — | — | EP | disclosed |
| EP-0060426-A2 | N-(2,2,2-trifluoroethyl)-N-alkyl-azolyloxyacetic-acid amides, their preparation and use as herbicides and intermediates for their preparation | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |
| EP-0057872-A2 | Dihalogenated imidazole-2-carboxamides, process for their preparation and their herbicidal application | BAYER AG (DE) | 1982-08-18 | — | — | EP | disclosed |
| EP-0039813-A1 | Fluor-containing azomethines, preparation thereof and use thereof as intermediates | BAYER AG (DE) | 1981-11-18 | — | — | EP | disclosed |