SCHEMBL26853173

SCHEMBL26853173

CSCNC[C@@H](C)Oc1cc(F)cc(CCC(=O)C(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CYP4F2 P78329 1/20 0.35
▸ CYP4A11 Q02928 1/20 0.35
▸ FFAR4 Q5NUL3 1/20 0.34
▸ GCK P35557 3/20 0.32
▸ MTNR1A P48039 6/20 0.30
▸ MTNR1B P49286 6/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21472028 0.89 CYP4F2 (0.38) CYP4F2CYP4A11FFAR4GCKMTNR1A
SCHEMBL20443306 0.89 CYP4F2 (0.38) CYP4F2CYP4A11FFAR4GCKMTNR1A
SCHEMBL29329606 0.86 CYP4F2 (0.36) CYP4F2CYP4A11FFAR4GCKMTNR1A
SCHEMBL20133413 0.85 CYP4F2 (0.39) CYP4F2CYP4A11FFAR4GCKMTNR1A
SCHEMBL26030360 0.85 CYP4F2 (0.39) CYP4F2CYP4A11FFAR4GCKMTNR1A
SCHEMBL18592300 0.84 CYP4F2 (0.38) CYP4F2CYP4A11FFAR4GCKMTNR1A
SCHEMBL22560664 0.84 CYP4F2 (0.38) CYP4F2CYP4A11FFAR4GCKMTNR1A
SCHEMBL18592294 0.84 CYP4F2 (0.38) CYP4F2CYP4A11FFAR4GCKMTNR1A
SCHEMBL21025972 0.83 CYP4F2 (0.36) CYP4F2CYP4A11FFAR4GCKMTNR1A
SCHEMBL21982871 0.83 CYP4F2 (0.37) CYP4F2CYP4A11FFAR4GCKMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11834460-B2 Imide-based modulators of proteolysis and associated methods of use YALE UNIVERSITY (US) 2023-12-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834460-B2 Imide-based modulators of proteolysis and associated methods of use CRBN, MDM2, UBE2N CYP4F2 3657/4885CYP4A11 4117/4885FFAR4 4818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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