SCHEMBL26855355

SCHEMBL26855355

c1ccc(-c2cccc(-c3nc(-c4ccc5c(c4)sc4c(-n6c7ccccc7c7cc8ccccc8cc76)cccc45)nc4c3sc3ccccc34)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 4/20 0.34
LIMK2 P53671 2/20 0.33
PIM1 P11309 1/20 0.30
PIM3 Q86V86 1/20 0.30
PIM2 Q9P1W9 1/20 0.30
TNKS O95271 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26855358 0.97 LIMK1 (0.33) LIMK1LIMK2TNKSTNKS2ALOX5
SCHEMBL26855445 0.92 LIMK1 (0.33) LIMK1LIMK2
SCHEMBL26855344 0.90 LIMK1 (0.34) LIMK1LIMK2
SCHEMBL26855075 0.88 LIMK1 (0.35) LIMK1LIMK2TNKSTNKS2ALOX5
SCHEMBL26855448 0.88 LIMK1 (0.32) LIMK1
SCHEMBL26855346 0.87 LIMK1 (0.32) LIMK1LIMK2
SCHEMBL26855082 0.87 LIMK1 (0.34) LIMK1LIMK2
SCHEMBL23740558 0.86 PRKDC (0.33)
SCHEMBL26855050 0.85 LIMK1 (0.32) LIMK1LIMK2TNKSTNKS2ALOX5
SCHEMBL23740357 0.85 LIMK1 (0.31) LIMK1PIM1PIM3PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230380283-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO.,LTD. (KR) 2023-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230380283-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE CYP1B1, CYP4F11, NOTUM LIMK1 356/4885LIMK2 1051/4885PIM1 794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.